45 psi is a notable deviation from factory recommendations of 28/36: 60% higher in front and 25% higher in back than factory. Why do you choose to run higher pressures and what have your results been?
Higher pressures:
Taller tires have taller sidewalls, hence running them at near-factory pressures will make them handle sloppily on the highway. An emergency avoidance maneuver is a "no big deal" with high pressure, and scary as shit at 28-35 psi.
In a similar sense, 225/75 will handle better at higher pressures than 235/70.
The higher is the pressure, the less likely the tire is unseated off the rim in a side drift.
As a side benefit, tires with higher pressures are less likely to be damaged by an accidental obstacle like an edge of a curb or a brick on the road (or by sharp rocks off pavement).
Front/Rear:
After installing the front TT, I was horrified by the handling of my D1. The sudden change in road slope in conjunction with a curve appeared as an abrupt switch from a severe understeer to severe oversteer. A simple solution to that, suggested by someone on DWeb (and confirmed by an independent source) was to run the front tires at the same pressure as the rears. In effect, it reduced the straight-line understeer, and as a consequence - transition to oversteer.
The numbers themselves depend greatly on the type of tire used. My LR4, for instance, has C-rated tires with max pressure of 50 psi - so I don't pump them over 42. The guys who run versions of Michelin X with rock-hard sidewalls prefer lower pressures.