I'll need to know your budget, items to be contained, their levels of durability and required care, manner of travel, expected travel and use conditions upon your arrival and, importantly, your expected method of return.
You should stretch your budget as far as possible when considering travel gear, so think as high as you can. Odds are, you'll only buy it once. It's reliability and performance are directly responsible for convenience and efficiency of operation. That can be the difference between easy operation and a royal pain in the ass that holds you back at every turn.
You don't want to spend this kind of money on a royal pain in the ass.
If you want, you can PM me to arrange a more direct consultation and free exchange of information. For now, there is one travel accessory that I encourage everyone to include in their loadout:
The shoulder bag. Acquire it, learn it, and use it. I bartered this when new as payment for an inconvenient task in the military, and have used it the world over to great effect. It's been repaired several times, but it works. There are good civilian options available, one of which I own.
Edit: If you wonder how such an item could be useful in common travel, I'll tell you.
Consider the things you might carry through an airport to be used upon arrival. You might have sunglasses, a mobile phone of some kind, keys, a watch, various jewelry, a wallet, passport, flight documentation, perhaps a book, cigarettes and whatever else may be carried and needed at the ready upon arrival.
The secondary benefit is the best. If those things are in various pockets, worn, or otherwise arrayed about your person, you'll spend time buggering around at security, perhaps misplace them, or they might become a discomfort during flight. If it's all in an easily accessed bag, you simply toss it in the box and pick it up on the other side of the checkpoint.
Upon reaching your destination, simply re-pimp yourself and stuff the bag in your normal carry-on luggage. Or strap her on, fill her with stuff that matters, and go get dirty in a pleasantly unfortunate environment.
There is a tertiary benefit as well. It's a way to cheat the carry-on regulations. You've got your normal carry-on bag, perhaps a laptop, and a shoulder bag. The shoulder bag doesn't count.
Cheers,
Kennith